Recent Progenra Publications

Strategies for the Identification of Ubiquitin Ligase Inhibitors. Goldenberg SJ, Marblestone JG, Mattern MR and Nicholson B. Biochem Soc Trans (In Press)

Detection and characterization of deSUMOylase activity using a novel, sensitive reporter assay.
Leach, CA, Tian, X, Mattern, MR and Nicholson, B. 2009. In Methods in Molecular Biology- SUMO Protocols, Ullrich, H, ed. Humana Press, 497:269-81

Strategies for the Identification of novel inhibitors of deubiquitinating enzymes
Seth J Goldenberg, Jeffrey L McDermott, Tauseef R Butt, Michael R Mattern and Benjamin Nicholson. 2008, Transactions in Biochemistry, Oct;36 (Pt 5):828-32

Characterization of Ubiquitin and Ubiquitin-like Protein Isopeptidase Activities.
Nicholson, Benjamin, Leach, Craig A, Goldenberg, Seth J, Francis, Dana M, Kodrasov, Matthew P, Tian, Xufan, Shanks, John, Sterner, David E, Bernal, Alejandro, Mattern, Michael R, Wilkinson, Keith D, and Butt, Tauseef R. 2008. Protein Science, 17: 1035-1043

Deubiquitinating Enzymes as Novel Anticancer Targets.
Nicholson, Benjamin, Marblestone, Jeffrey G, Butt, Tauseef R, and Mattern, Michael R. 2007. Future Oncology, 3: 191-199.

SUMO isopeptidase assay based on poliovirus RNA polymerase activity.
Arnold, JJ, Bernal, A, Uche, U, Sterner, DE, Butt, TR, Cameron, CE, and Mattern, MR. 2006 Analytical Biochem, 350: 214-221.

Comparison of SUMO Fusion Technology with Traditional Gene Fusion System: Effects of Recombinant Protein Expression and Purification.
Marblestone, J. Edavettal, S., Lim, Y,. Lim, P., Zuo, X., Butt, T. R. (2006) Protein Science 15:182-189.