Dedicated to finding new medicines for a variety of diseases by targeting the ubiquitin pathway, a critical mechanism of cellular regulation. Using our UbiPro™ Discovery Platform we have identified selective inhibitors of critical ubiquitin pathway enzymes associated with cardiovascular disease, cancer and other debilitating diseases. This technology and multiple selective compounds are available for licensing.
Progenra’s goal is to discover novel drugs targeting the ubiquitin pathway using their proprietary technology.
E3 LIGASE TECHNOLOGY
Progenra is seeking industry partnerships for licensing opportunities surrounding the company’s small molecule portfolio and/or its proprietary UbiPro™ Drug Discovery Platform.
Researchers at Progenra, Inc. announce the advanced online publication of the article “Selective Dual Inhibitors of the Cancer-related Deubiquitylating Proteases USP7 and USP47” (Weinstock, J. et al, ACS Medicinal Chemistry Letters). The new article presents evidence of a therapeutic benefit resulting from dual inhibition of USP7 and a related enzyme, USP47.